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Re: Standards for inclusion/exclusion criteria ?

From: Jiang, Guoqian, M.D., Ph.D. <Jiang.Guoqian@mayo.edu>
Date: Mon, 15 Jul 2013 01:39:07 +0000
To: Andrea Splendiani <andrea.splendiani@deri.org>, "public-semweb-lifesci@w3.org HCLS" <public-semweb-lifesci@w3.org>
CC: "Solbrig, Harold R." <Solbrig.Harold@mayo.edu>
Message-ID: <CE08B8AD.677C%jiang.guoqian@mayo.edu>
Hi, Andrea,

You may want to look into the clinical element models developed for
normalization of EMR data for secondary use in the ONC SHARP project,
including the models of patients, disease/disorder, noted drug and lab
observations. The models are rendered in XML schema format.


In addition, there is an international effort known as the Clinical
Information Modeling Initiative (CIMI) in the standardization of clinical
information models, in which CDISC, HL7 and may other organizations are
participating in.




Guoqian Jiang
Mayo Clinic

On 7/14/13 6:34 PM, "Andrea Splendiani" <andrea.splendiani@deri.org> wrote:

>I was wondering if somebody could provide some pointer to work going on
>in an area that is related to clinical trials: inclusion and exclusion
>(I have followed the recent thread on encoding Hamilton Disease and
>In, particular, I am interested in two things:
>Standards with substantial uptake (sub question: is CDISC's uptake actual
>or perspective ?).
>Modeling of inclusion/exclusion criteria, but with a particular twist:
>not modeling the questions, but the facts that are queried. Basically I
>am interested in modeling patients and conditions (to the level of detail
>required "usually" required by clinical trials). The subject itself can
>be very vast, but is there a framework which provides at least an upper
>perspective on how to model subjects's features, diseases, interventions,
>samples (also respect to time) ?
>Any pointer is welcome!
>Andrea Splendiani
Received on Monday, 15 July 2013 01:39:32 UTC

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