- From: Mark <markw@illuminae.com>
- Date: Tue, 27 Jul 2010 09:34:35 -0700
- To: "obo-discuss@lists.sourceforge.net" <obo-discuss@lists.sourceforge.net>, "public-semweb-lifesci@w3.org" <public-semweb-lifesci@w3.org>, Michel_Dumontier <Michel_Dumontier@carleton.ca>
Hey Michel, > 1 - What metrics should we use to assess ontology quality and determine > whether an ontology is "good". Ben Good took a stab at this with the OntoLoki project (see chapter in Ben's thesis starting on page 61 http://circle.ubc.ca/bitstream/handle/2429/7115/ubc_2009_spring_good_benjamin.pdf)... Ben, Chris Mungall, Soroush Samadian and I have been discussing perhaps resurrecting the project and working together on finishing it... though we're questioning whether it is really useful for evaluating an ontology, versus bootstrapping the DL-ification of OBO-style ontologies. > 2 - Can we re-factor existing, and well used terminologies (SNOMED-CT, > NCI-T, ICD) into "good" ontologies for health care and the life sciences? OntoLoki speaks to this issue also (see link above), and as soon as Soroush finishes his PhD candidacy exam in 2 weeks, we'll be writing and submitting a paper on how we have re-factored the cardiovascular part of GALEN - we can send you a draft of that as soon as it is ready. The re-factoring was done manually in this case, but we plan to use OntoLoki-style pattern-discovery in the future to see if we can at least partically automate the process. Part of soroush's thesis project is to connect OntoLoki to the iCAPTURER (an Elisa-style Q&A interface) to see if we can combine pattern discovery with human-expert validation simultaneously to allow end-users to create their own DL ontologies. if any of this is helpful let me know and I'll send you whatever we have :-) Mark -- Mark Wilkinson Assistant Professor, Medical Genetics PI Bioinformatics, Heart + Lung Institute @ St. Paul's Hospital University of British Columbia Vancouver, BC Canada
Received on Tuesday, 27 July 2010 16:35:09 UTC