RE: Encoding the Hamilton Depression Rating Scale..

Tonya, Alfredo and I did some work related to modeling clinical
documentation questionnaires - presented at ISWC 2005.

 

http://scholar.google.com/scholar?cluster=7780078922780239485&hl=en&as_sdt=0
,7 

 

The key issue here was to "separate" out the following:

1. Presentation UI elements

2. The ontology capturing the question-answer and nesting structure

3. The clinical ontology capturing diseases etc.

 

Hope this is useful.

 

Cheers,

 

---Vipul

 

From: Luciano, Joanne S. [mailto:luciaj2@rpi.edu] 
Sent: Friday, July 12, 2013 11:52 AM
To: Kerstin Forsberg
Cc: public-semweb-lifesci hcls; Brendan Ashby
Subject: Re: Encoding the Hamilton Depression Rating Scale..

 

 

On Jul 10, 2013, at 11:37 PM, Kerstin Forsberg
<kerstin.l.forsberg@gmail.com>

 wrote:





Hi Joanne, 

I'm intrerested in learning more about SIO and it's potential for clinical
data. 

 

Michel is the expert on SIO.  The web page is here:
http://code.google.com/p/semanticscience/wiki/SIO

I can tell you more after we encode the Hamilton Scale. 

 

Thanks very much for the link below. I will pass it along to my student.

 

Kind regards,

Joanne





 

I can think of two related, and quite, different approaches:

 

- CDISC provide some pieces of standards for questionnaires, such as
Hamilton scale (e.g.. the list of text strings to identify different
questions
http://evs.nci.nih.gov/ftp1/CDISC/Questionnaire/QS%20Terminology.html), A
FDA/Phuse project for Semantic Technology work on representing these pieces
in RDF (http://cdisc2rdf.com/). CDISC together with TransCelerate BioPharma
plan to tie the different pieces of together for measurements and
questionaries as so called "Scientific Concepts" as part of thw SHARE
project (http://www.cdisc.org/cdisc-share)

 

- At ICBO eralier this week presented Alan Ruttenberg with collegues in
Buffalo an interesting paper on a OBO Foundry based approach for another
clinical instrument, i,e the Mini Mental Scale (MMSE), "Measuring Cognitive
Functions: Hurdles in the Development of the NeuroPsychological Testing
Ontology"
http://www.unbsj.ca/sase/csas/data/ws/icbo2013/papers/research/icbo2013_subm
ission_46.pdf 

 

Kind Regards

Kerstin

2013/7/10 Luciano, Joanne S. <luciaj2@rpi.edu>

Looking for some thoughts on this.

 

 

We're creating an ontology for the hamilton depression rating scale (this is
the clinical instrument used in all clinical trials of antidepressants).

 

 

Would it be good to build this under SIO?

 

if so, where i think it fits, is under process (the depression treatment is
a process)

process-> interaction->observation->

 

adding sub classes there

instrument 

    clinical instrument

             Hamilton Depression Rating Scale 

                     HDRS 28 Question Version 

                           Q1-Depressed mood 

                           [etc]

 

does this make sense to you? 

do you have a better idea?

 

 

Thanks,

Joanne