- From: Kei Cheung <kei.cheung@yale.edu>
- Date: Sun, 01 Nov 2009 08:44:40 -0500
- To: Jun Zhao <jun.zhao@zoo.ox.ac.uk>
- CC: mdmiller <mdmiller53@comcast.net>, Helen Parkinson <parkinson@ebi.ac.uk>, HCLS <public-semweb-lifesci@w3.org>, Tony Burdett <tburdett@ebi.ac.uk>
Hi Jun et al, The following gene list: http://public.tgen.org/tgen.org/supplementarydata/neurogenomics/supplementarydata/brain_regions/PCA1_0_98_correlation.xls was gereated using the Principal components analysis (PCA). It is an annotated list of 102 genes showing at least a 0.98 correlation to PCA1 (first principal component). This is part of the following paper: http://www.ncbi.nlm.nih.gov/pubmed/17077275?dopt=Abstract I'm airport t to the airport now ... Cheers, -Kei Jun Zhao wrote: > Hello Michael, > > Sorry I didn't see this email from you since I have been traveling. > > I am aware of the scovo vocabulary. Actually scovo is used in the voiD > [1] vocabulary to describe statistics about data and I am one member > of the voiD working group. Although scovo is a well-designed model to > serve its purpose, we have found that it is quite difficult to query > for datasets using this vocabulary. Hence, in the current voiD working > group, proposing an alternative model to describe statistics of > datasets has been a high priority. We are planning to release voiD2.0 > including a new statistics model around Christmas. It would be nice if > I can gather more user requirements from you and people on this list.:) > > [1] http://rdfs.org/ns/void-guide > > Best, > > Jun > > mdmiller wrote: > >> hi all, >> >> on a different HCLS thread i saw this proposal from jeni tennison for >> specifying a generic dataset, it might be a useful way to encode a >> list of differentially expressed genes. it looks like one could do >> this encoding on the fly, so that the data itself at the source could >> be in whatever format is natural. >> >> http://sw.joanneum.at/scovo/schema.html >> >> cheers, >> michael >> >> Michael Miller >> mdmiller53@comcast.net >> >> ----- Original Message ----- From: "Kei Cheung" <kei.cheung@yale.edu> >> To: "Helen Parkinson" <parkinson@ebi.ac.uk> >> Cc: "HCLS" <public-semweb-lifesci@w3.org>; "Tony Burdett" >> <tburdett@ebi.ac.uk> >> Sent: Wednesday, October 14, 2009 7:03 PM >> Subject: Re: Action Items from call today >> >> >>> Thanks, Helen. >>> >>> To make it more concrete. I've been thinking about some example >>> queries that I hope can be answered by the RDF data once converted. >>> I wonder if the following example quereis can be answered: >>> >>> Retrieve a list of differentially expressed genes between different >>> brain regions (e.g., hippocampus and entorhinal cortex) for normally >>> aged human subjects. >>> >>> Retrieve a list of differentially expressed genes for the same brain >>> region of normal human subjects and AD patients. >>> >>> Using these lists of genes one can issue (federated) queries to >>> retrieve addtional information about the genes for various types of >>> analyses (e.g., GO term enrichment). >>> >>> Just a thought. >>> >>> Cheers, >>> >>> -Kei >>> >>> >>> >>> Helen Parkinson wrote: >>> >>>> Hi >>>> >>>> here are my action items from the call today >>>> >>>> 1. MAGE-TAB->RDF, Lena requested details. >>>> >>>> Code here: https://sourceforge.net/projects/limpopo/ >>>> >>>> Java Parser for MAGE-TAB developed by EBI, used by several groups. >>>> Contact Tony Burdett tburdett@ebi.ac.uk for details. Tony estimates >>>> for a simple RDF dump a few days work. Lena if you are interested >>>> in working on this java code please contact Tony as he's already >>>> designed with rdf export in mind >>>> >>>> 2. MAGE-TAB->MAGE-ML - code from Junmin Liu at UPenn >>>> >>>> https://sourceforge.net/projects/tab2mage/files/ - see mage2tab >>>> Pretty much all public MAGE-ML comes from AE and is available from >>>> Arrayexpress ftp dirs as mage-tab already. Exceptions are Rosetta's >>>> mage-ml importer, and non public data >>>> >>>> >>>> 3. EBI experimental factor ontology (EFO) slides, attached >>>> see also www.ebi.ac.uk/efo >>>> >>>> 4. Noted that an RDF dump of atlas data and triple store access >>>> will be useful, we'll announce when these are available >>>> >>>> thanks >>>> >>>> Helen >>>> >>>> >>>> >>> >>> >> >> >> >> > >
Received on Sunday, 1 November 2009 13:45:16 UTC