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From: kc28 <kei.cheung@yale.edu>
Date: Thu, 16 Mar 2006 21:50:58 -0500
To: 'public-semweb-lifesci' <public-semweb-lifesci@w3.org>
Message-id: <441A2412.1030508@yale.edu>


I have written a proposal of the SenseLab task, which is described at 
the following URL:


The SenseLab project (http://senselab.med.yale.edu/senselab/) is a long 
term effort that builds integrated, multidisciplinary models of neurons 
and neural systems, using the olfactory pathway as a model.  This is one 
of a number of projects funded as part of the Human Brain Project 
(http://www.nimh.nih.gov/neuroinformatics/index.cfm) whose aim is to 
develop neuroinformatics tools in support of neuroscience research. The 
project involves novel informatics approaches to constructing databases 
and database tools for collecting and analyzing neuroscience 
information, and providing for efficient interoperability with other 
neuroscience databases. Recently, a new subdatabase called BrainPharm is 
under development within SenseLab, which supports research on drugs for 
the treatment of different neurological disorders. It contains agents 
that act on neuronal receptors and signal transduction pathways in the 
normal brain and in nervous disorders. It enables searches for drug 
actions at the level of key molecular constituents, cell compartments 
and individual cells, with links to models of these actions. Currently 
the SenseLab database is implemented using Oracle.

The SenseLab project is listed in the Neuroscience Database Gateway 
(NDG) (http://big.sfn.org/NDG/site/). In fact, the SenseLab team is 
involved in building NDG. I also talked to Dr. Gordon Shepherd, who is a 
neuroscientist and the PI of SenseLab, about our semantic web effort. He 
said that he would be willing to join some of our future conference 
calls to provide his input if needed. Please let me know if the SenseLab 
task fits the interest of the BioRDF group. Please let me know if you 
have any comments/feedback.


Received on Friday, 17 March 2006 02:56:58 UTC

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