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- Date: Mon, 5 Jun 2006 22:56:28 -0400
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One example of why you want to use the same neuroanatomical ontology as the practicing neuroanatomists do. (See citing papers.) Skip Navigation Oxford Journals Contact Us My Basket My Account Cerebral Cortex About This Journal Contact This Journal Subscriptions Current Issue Archive Search Oxford Journals Life Sciences Cerebral Cortex Volume 8, Number 4 Pp. 372-384 This Article FREE Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Add to My Personal Archive Download to citation manager Cited by other online articles Search for citing articles in: ISI Web of Science (77) Request Permissions Google Scholar Articles by Kennedy, D. N. Articles by Caviness, V. S. PubMed PubMed Citation Articles by Kennedy, D. N. Articles by Caviness, V. S., Jr Cerebral Cortex, Vol 8, 372-384, Copyright © 1998 by Oxford University Press ARTICLES Gyri of the human neocortex: an MRI-based analysis of volume and variance DN Kennedy, N Lange, N Makris, J Bates, J Meyer and VS Caviness Jr Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA. dave@cma.mgh.harvard.edu This magnetic resonance imaging (MRI)-based morphometric analysis of cortical topography in the human brain is based upon the segmentation and parcellation of volumetric T1-weighted MRI data for a set of 20 young adult brains including 10 males and 10 females. For the most part, each parcellation unit (PU) of the neocortex corresponds to a single or a portion of a single gyrus. The volumes of each PU were computed for each brain. Subsets of PUs were also grouped so as to represent the neocortex for the frontal, temporal, parietal and occipital lobes. The coefficient of variation of the mean volume of total neocortex and that of the neocortex assigned to individual lobes cluster around 10%, whereas that of neocortex assigned to the individual gyri (PU) is more than twice that value. Approximately 80% of the total variance in gyral volume arises from determinants interactive for individual and specific gyri, while only approximately 10% of the total variance appears to be a reflection of uniform scaling to total neocortical volume. Sexual dimorphism contributes a pervasive though relatively small component of this variance. These results have implications for the study of structure- function correlation, and the proper statistical methods of handling volumetric data in morphometric studies. In addition, the nature of the covariance structure of the data will lead to future hypotheses regarding the relationships between the various potential genetic and epigenetic gyral influencing factors. This article has been cited by other articles: A. Mechelli, K. J. Friston, R. S. Frackowiak, and C. J. Price Structural Covariance in the Human Cortex J. Neurosci., September 7, 2005; 25(36): 8303 - 8310. [Abstract] [Full Text] [PDF] J. A. Frazier, S. Chiu, J. L. Breeze, N. Makris, N. Lange, D. N. Kennedy, M. R. Herbert, E. K. Bent, V. K. Koneru, M. E. Dieterich, S. M. Hodge, S. L. Rauch, P. E. Grant, B. M. Cohen, L. J. Seidman, V. S. Caviness, and J. Biederman Structural Brain Magnetic Resonance Imaging of Limbic and Thalamic Volumes in Pediatric Bipolar Disorder Am J Psychiatry, July 1, 2005; 162(7): 1256 - 1265. [Abstract] [Full Text] [PDF] M. R. Herbert, D. A. Ziegler, C. K. Deutsch, L. M. O'Brien, D. N. Kennedy, P. A. Filipek, A. I. Bakardjiev, J. Hodgson, M. Takeoka, N. Makris, and V. S. Caviness Jr Brain asymmetries in autism and developmental language disorder: a nested whole-brain analysis Brain, January 1, 2005; 128(1): 213 - 226. [Abstract] [Full Text] [PDF] M. Takeoka, J. J. Riviello Jr., F. H. Duffy, F. Kim, D. N. Kennedy, N. Makris, V. S. Caviness Jr., and G. L. Holmes Bilateral volume reduction of the superior temporal areas in Landau- Kleffner syndrome Neurology, October 12, 2004; 63(7): 1289 - 1292. [Abstract] [Full Text] [PDF] B. S. Peterson, A. W. Anderson, R. Ehrenkranz, L. H. Staib, M. Tageldin, E. Colson, J. C. Gore, C. C. Duncan, R. Makuch, and L. R. Ment Regional Brain Volumes and Their Later Neurodevelopmental Correlates in Term and Preterm Infants Pediatrics, May 1, 2003; 111(5): 939 - 948. [Abstract] [Full Text] [PDF] C. U. Lee, M. E. Shenton, D. F. Salisbury, K. Kasai, T. Onitsuka, C. C. Dickey, D. Yurgelun-Todd, R. Kikinis, F. A. Jolesz, and R. W. McCarley Fusiform Gyrus Volume Reduction in First-Episode Schizophrenia: A Magnetic Resonance Imaging Study Arch Gen Psychiatry, September 1, 2002; 59(9): 775 - 781. [Abstract] [Full Text] [PDF] V. S. Caviness, N. Makris, E. Montinaro, N. T. Sahin, J. F. Bates, L. Schwamm, D. Caplan, and D. N. Kennedy Anatomy of Stroke, Part I: An MRI-Based Topographic and Volumetric System of Analysis Stroke, November 1, 2002; 33(11): 2549 - 2556. [Abstract] [Full Text] [PDF] B. S. Peterson, L. Staib, L. Scahill, H. Zhang, C. Anderson, J. F. Leckman, D. J. Cohen, J. C. Gore, J. Albert, and R. Webster Regional Brain and Ventricular Volumes in Tourette Syndrome Arch Gen Psychiatry, May 1, 2001; 58(5): 427 - 440. [Abstract] [Full Text] [PDF] H. D. Rosas, J. Goodman, Y. I. Chen, B. G. Jenkins, D. N. Kennedy, N. Makris, M. Patti, L. J. Seidman, M. F. Beal, and W. J. Koroshetz Striatal volume loss in HD as measured by MRI and the influence of CAG repeat Neurology, September 25, 2001; 57(6): 1025 - 1028. [Abstract] [Full Text] [PDF] C. I. Moore, C. E. Stern, C. Dunbar, S. K. Kostyk, A. Gehi, and S. Corkin Referred phantom sensations and cortical reorganization after spinal cord injury in humans PNAS, December 19, 2000; 97(26): 14703 - 14708. [Abstract] [Full Text] [PDF] P. M. Thompson, M. S. Mega, R. P. Woods, C. I. Zoumalan, C. J. Lindshield, R. E. Blanton, J. Moussai, C. J. Holmes, J. L. Cummings, and A. W. Toga Cortical Change in Alzheimer's Disease Detected with a Disease- specific Population-based Brain Atlas Cereb Cortex, January 1, 2001; 11(1): 1 - 16. [Abstract] [Full Text] M. Yücel, G. W. Stuart, P. Maruff, D. Velakoulis, S. F. Crowe, G. Savage, and C. Pantelis Hemispheric and Gender-related Differences in the Gross Morphology of the Anterior Cingulate/Paracingulate Cortex in Normal Volunteers: An MRI Morphometric Study Cereb Cortex, January 1, 2001; 11(1): 17 - 25. [Abstract] [Full Text] C. I. Moore, C. E. Stern, S. Corkin, B. Fischl, A. C. Gray, B. R. Rosen, and A. M. Dale Segregation of Somatosensory Activation in the Human Rolandic Cortex Using fMRI J Neurophysiol, July 1, 2000; 84(1): 558 - 569. [Abstract] [Full Text] M. E. Frederikse, A. Lu, E. Aylward, P. Barta, and G. Pearlson Sex Differences in the Inferior Parietal Lobule Cereb Cortex, December 1, 1999; 9(8): 896 - 901. [Abstract] [Full Text] Online ISSN 1460-2199 - Print ISSN 1047-3211 Copyright © 2006 Oxford University Press Oxford Journals Oxford University Press Site Map Privacy Policy Frequently Asked Questions Other Oxford University Press sites:
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