Re: Requesting feedback on draft Community Group Report about a minimum representation of potential drug-drug interaction knowledge and evidence

Hi Richard and all,

Hopefully there is still time to consider including something about the
following in your report.

There's an online system  that supports writing and running of
self-explaining data apps, specified in open vocabulary English.

Here's a summary slide about the system --
https://www.executable-english.com/internet_business_logic_in_a_nutshell.pdf

One of the example applications of the system is a set of English
statements that describes drug-drug interactions, using a significant
database.

Here's an example executable English statement:

the drug brand some-BrandID1 some-name1 has an active ingredient
some-IngredientID1 some-IDescr1
the drug brand some-BrandID2 some-name2 has an active ingredient
some-IngredientID2 some-IDescr2
that-BrandID1 is not equal that-BrandID2
that-IngredientID1 is not equal that-IngredientID2
that-IngredientID1 interacts with that-IngredientID2 as described by
some-IIText
---------------------------------------------------------------------------------------------------------------
the drugs that-name1 and that-name2 have active ingredients that interact

A collection of such statements that can be run directly (without further
'programming') is at
https://www.executable-english.com/demo_agents/HclsDrugDb1.agent

There's also a short video about the system and this application at
https://www.executable-english.com/ibldrugdbdemo1.htm

I hope this may be of interest. Thanks for comments, and apologies to folks
who have seen this before.

                                                        -- Adrian
Adrian Walker
Executable English LLC
San Jose, CA, USA
(USA) 860 830 2085 (California time)
www.executable-english.com

PS:  The link http://localhost/~rdb20/hcls-drug-drug-interaction/ seems to
be broken <http://localhost/~rdb20/hcls-drug-drug-interaction/>




On Sat, Feb 23, 2019 at 10:54 AM Boyce, Richard David <rdb20@pitt.edu>
wrote:

> Hello,
>
> Would anyone interested please take a look at our draft Semantic Web in
> Health Care and Life Sciences Community Group Report?  It is  titled
> "Minimum Representation of Potential Drug-Drug Interaction Knowledge and
> Evidence - Technical and User-centered Foundation Specification." The
> abstract of this Report is copied below. The Report  is the culmination
> of more than 2 years of effort by a volunteer multidisciplinary task
> force. We feel that this is very close to being ready to publish.
>
> The full draft of the note is located here:
>
> http://localhost/~rdb20/hcls-drug-drug-interaction/
>
> Feel free to email feedback to this list or post issues on the project's
> github: https://github.com/w3c/hcls-drug-drug-interaction/
>
> Abstract:
>
> The purpose of this Community Group Note is to provide a technical and
> user-centered foundation for a minimum information model for information
> about potential drug-drug interactions. The Note provides non-ambigous
> definitions for 10 core information items. It also provides 8 detailed
> best practice recommendations related to the 10 core information items.
> The definitions and recommendations are shown as both narrative and
> prototype JSON artifacts using 2 exemplar potential drug-drug
> interactions. Adoption of the recommendations by developers of PDDI
> knowledge artifacts will improve the usefulness of the artifacts within
> clinical workflows. Intended downstream applications include clinical
> decision support, drug product label enhancement, cohort identification,
> and other activities relevant to protecting patients from harm from drug
> interactions.
>
>
> --
> Richard D Boyce, PhD
> Associate Professor of Biomedical Informatics and Clinical and
> Translational Science in the Clinical and Translational
> Science Institute
> Director of the Informatics Core for the Center of Excellence for Natural
> Product- Drug Interaction Research (NaPDI)
> Faculty, Center for Pharmaceutical Policy and Prescribing
> Faculty, Geriatric Pharmaceutical Outcomes and Gero-Informatics Research
> and Training Program
> University of Pittsburgh
> rdb20@pitt.edu
> Office: 412-648-9219
> Twitter: @bhaapgh
>
>