SPOKE (aka HetioNet) and bioschemas

Has anyone done (or would be interested to do) a compare/contrast of SPOKE
(previously HetioNet) and the bioschemas designs?

To give a rough idea, it seems to have types for: Gene, Disease,
Pathway, PharmacologicClass, CellularComponent, Compound, Anatomy,
Symptom, BiologicalProcess, MolecularFunction, SideEffect.

https://neo4j.het.io/browser/ is a neo4j-powered browser (try "CALL
db.schema()"), and https://elifesciences.org/articles/26726 a summary, with
the schema in this section: https://elifesciences.org/articles/26726#s4

Does it seem reasonable that this level of detail might be mixed directly
in alongside schema.org+bioschemas markup along the lines recently
discussed from blue brain e.g.
https://github.com/BlueBrain/nexus-bbp-domains/blob/master/modules/bbp-experiment/src/main/resources/schemas/bbp/experiment/subject/v0.1.0.json
?

cheers,

Dan