- From: Waclaw Kusnierczyk <Waclaw.Marcin.Kusnierczyk@idi.ntnu.no>
- Date: Thu, 19 Jul 2007 21:42:03 +0200
- To: public-semweb-lifesci@w3.org
Darren Natale wrote: > > Protein, in this scheme, is the amino acid polymer produced by a > translation process using an mRNA as a template. This fits about any polypeptide produced by a ribosome. I'd think that the term 'protein' is reserved for some, but not all polypeptides (even if we talk only about those produced by ribosomes). Interestingly, Lodish et al. [1] say, "we reserve the term protein for a polypeptide (or a complex of polypeptides) that has a three-dimensional structure". I just can't imagine a polypeptide that does not have a three-dimensional structure -- even if it is ideally linearly stretched (which is rarely the case in a cell). I guess they mean tertiary structure. Lots of nice problems lurking here. > I suppose this > excludes peptides (also amino acid polymers) that are produced > non-ribosomally, but perhaps that is okay for the time being. The > precise definition will be constructed with input from the Sequence > Ontology curators. Do you consider SO a source of precise definitions? vQ [1] Lodish et al. (2000). Molecular Cell Biology. Freeman and Co.
Received on Thursday, 19 July 2007 19:42:22 UTC