Re: Encoding the Hamilton Depression Rating Scale….

Hi Joanne,
I'm intrerested in learning more about SIO and it's potential for clinical
data.

I can think of two related, and quite, different approaches:

- CDISC provide some pieces of standards for questionnaires, such as
Hamilton scale (e.g.. the list of text strings to identify different
questions
http://evs.nci.nih.gov/ftp1/CDISC/Questionnaire/QS%20Terminology.html), A
FDA/Phuse project for Semantic Technology work on representing these pieces
in RDF (http://cdisc2rdf.com/). CDISC together with TransCelerate BioPharma
plan to tie the different pieces of together for measurements and
questionaries as so called "Scientific Concepts" as part of thw SHARE
project (http://www.cdisc.org/cdisc-share)

- At ICBO eralier this week presented Alan Ruttenberg with collegues in
Buffalo an interesting paper on a OBO Foundry based approach for another
clinical instrument, i,e the Mini Mental Scale (MMSE), "Measuring Cognitive
Functions: Hurdles in the Development of the NeuroPsychological Testing
Ontology"
http://www.unbsj.ca/sase/csas/data/ws/icbo2013/papers/research/icbo2013_submission_46.pdf


Kind Regards
Kerstin

2013/7/10 Luciano, Joanne S. <luciaj2@rpi.edu>

>  Looking for some thoughts on this…
>
>
>  We're creating an ontology for the hamilton depression rating scale
> (this is the clinical instrument used in all clinical trials of
> antidepressants).
>
>
>  Would it be good to build this under SIO?
>
>  if so, where i think it fits, is under process (the depression treatment
> is a process)
> process-> interaction->observation->
>
>  adding sub classes there
> instrument
>     clinical instrument
>              Hamilton Depression Rating Scale
>                      HDRS 28 Question Version
>                            Q1-Depressed mood
>                            [etc]
>
>  does this make sense to you?
> do you have a better idea?
>
>
>  Thanks,
> Joanne
>