NCBO Webinar: Maryann Martone, Feb. 16

The next NCBO Webinar will be presented by Dr. Maryann Martone from UCSD on
"Ontology-based annotation of neurodegenerative disease phenotypes using the
Neuroscience Information Framework" at 10:00am PST, Wednesday, February 16.
Below is information on how to join the online meeting via WebEx and
accompanying teleconference. For the full schedule of the NCBO Webinar
presentations see: http://www.bioontology.org/webinar-series.

ABSTRACT:
In this presentation, Dr. Martone will show how structured annotations of
phenotypes created using community ontologies can be used to compare across
animal models and human neurodegenerative disease. We have created a
flexible template for creating multiscale phenotypes using the the
Neuroscience Information Framework (NIF;  http://neuinfo.org) and the PATO
ontologies. The basic model has been used to annotate phenotypes from
published articles and has been incorporated into a set of web-based tools
developed for annotation of very large multispectral imaging data sets
available through the Cell Centered Database (http://ccdb.ucsd.edu). The
goal is to establish tools and strategies that link phenotypes across
anatomical scales and structures through the use of both reasoning and
statistical measures.

SPEAKER BIO:
Maryann Martone received a B.A. from Wellesley College in biological
psychology and Ancient Greek, and her Ph.D. in neuroscience in 1990 from the
University of California, San Diego. Her thesis work on the neurochemical
organization of the mammalian neostriatum was performed in the laboratory of
Dr. Philip Groves. After receiving her degree, she joined the National
Center for Microscopy and Imaging Research, then newly founded at the
University of California, San Diego by Dr. Mark Ellisman. The National
Center is an NIH-established research resource dedicated to the advancement
of 3D multiscale imaging technologies for unraveling the molecular and
structural complexity of the nervous system. She is currently the
co-driector of the National Center and a Professor-in-Residence in the
Department of Neuroscience at UCSD.
Although she continues to investigate the structure of the nervous system
using light and electron microscopy, for the past several years, she has
been involved in the creation neuroinformatics resources for neuroscience.
Dr. Martone is the principal investigator of the Neuroinformatics Framework
project, a national pilot project awarded by the NIH to establish a uniform
resource description framework for neuroscience. She is the head of the Cell
Centered Database project (www.ccdb.ucsd.edu), an on-line database for
electron tomography and correlated light and electron microscopic data. Her
recent work has focused on building ontologies for neuroscience to
facilitate data exchange and integration, and integrating such ontologies
into image analysis and data mining tools. She serves as the US scientific
representative to the International Neuroinformatics Coordinating Facility
(INCF). Within the INCF, she chairs the program on Ontologies for Neural
Structures.

WEBEX DETAILS:
Topic: NCBO Webinar Series
Date: Wednesday, February 16, 2011
Time: 10:00 am, Pacific Standard Time (San Francisco, GMT-08:00)
Meeting Number: 929 613 752
Meeting Password: ncbo

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1. Go to
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You can contact me at:
whetzel@stanford.edu


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Trish Whetzel, PhD
Outreach Coordinator
The National Center for Biomedical Ontology
Ph: 650-721-2378 <+16507212378>
whetzel@stanford.edu
http://www.bioontology.org



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