- From: Waclaw Kusnierczyk <Waclaw.Marcin.Kusnierczyk@idi.ntnu.no>
- Date: Thu, 19 Jul 2007 22:38:22 +0200
- To: public-semweb-lifesci@w3.org
Michel_Dumontier wrote: > Darren, > >> Also, while we recognize >> that there are different qualities that can be ascribed to a basically >> identical biochemical entity in different structural conformations or >> states of ligand binding, we are not attempting (at least in the >> beginning) to describe these structural conformations or bound vs >> unbound forms. > > Indeed, while conformation is an important quality of molecular > structure, it does not fundamentally change the nature of the molecule. > i.e. a protein in a bound or unbound state should still be considered > the same protein. what about denaturation? is the nature (what nature, by the way?) of a protein not fundamentally different in its native vs. denaturated state? vQ
Received on Thursday, 19 July 2007 20:46:02 UTC