- From: Kei Cheung <kei.cheung@yale.edu>
- Date: Mon, 08 Jan 2007 11:08:43 -0500
- To: William Bug <William.Bug@DrexelMed.edu>
- Cc: Susie Stephens <susie.stephens@oracle.com>, public-semweb-lifesci <public-semweb-lifesci@w3.org>, MaryAnn Martone <maryann@ncmir.ucsd.edu>, Jessica Turner <turnerj@uci.edu>
Hi All,
I tried to call the BioRDF conference, but I kept getting the message
saying my access code "246733" was incorrect.
Thanks,
-Kei
William Bug wrote:
> Hi All,
>
> Here is one Use Case to review for today thanks to the efforts of my
> colleagues on the BIRN Ontology Task Force, Maryann Martone and
> Jessica Turner. It is representative of the low-hanging fruit approach
> we are taking - one where minimal ontology-based annotation on large
> data sets using a semantic framework covering specific neuroscience
> domains will help us to progressively add more utility to the BIRN
> infrastructure appropriate to meet the needs of the broadest range of
> neuroscientists. This is also a neuroimaging Use Case, so it should
> dovetail nicely with the discussion Daniel Rubin will be leading.
>
> There are a considerable collection of Use Cases covering a wider
> range of topics from molecular data in mouse models to clinical
> assessments which we (the BIRN OTF) are now proceeding through to
> provide a sufficient amount of detail so as to help us more clearly
> define our semantic infrastructural requirements. I'll send more of
> these around later as they become available.
>
> Cheers,
> Bill
>
>
> *BIRN Use Case #1:** **Locating specific types of functional
> neuroimaging data sets through the BIRN infrastructure*
> A researcher wants to examine all fMRI datasets where the subject is
> given a working memory task. Through the simple web interface, the
> user enters “fMRI data and working memory task”. The BIRN mediator
> searches the BIRNLex lexicon+ontology framework to find those
> behavioral paradigms listed under working memory tasks. The mediator
> then dispatches a distributed query to those data repositories which
> have been registered to it in search of fMRI data where subjects have
> been administered these tasks. In order to understand the results in
> context, the web interface provides the relevant portion of the
> hierarchy and indexes each result to the relevant term.
>
> The mediator in this case performs two essential functions: 1) it
> allows a query to be issued across multiple data resources without the
> need to query each one separately; 2) it utilizes the knowledge
> contained in BIRNLex to expand the query beyond the specified term to
> find data that is relevant to the query.
>
> This use case requires a level of deeper integration than simple
> keyword indexing of data sources can provide, because the user is
> asking for only those scans from subjects that were given a working
> memory test. Simple keyword descriptions of a resource do not
> provide adequate information for performing this type of query. For
> example, the current description of the data content of the fMRI Data
> Center (www.fmridc.org <http://www.fmridc.org>) includes the following:
>
> anatomical / structural, behavioral.sensory performance.olfaction,
> neuroimaging.functional
>
> Keyword searching would be able to indicate the fMRI data center as
> one resource that might have relevant data but would not be able to
> return the specific data sets desired without the user performing an
> additional query and sorting through the results, weeding out all the
> false positives.
>
> The goal of the BIRN Infrastructure in this context is to provide
> enabling technology not only capable off-loading some of the more
> simple semantically-driven tasks normally carried out by an expert
> neuroscience investigator, but to also provide a general knowledge
> supplement to cover those sub-domains a given neuroscientist may not
> know in detail. This example demonstrates both such forms of
> cognitive augmentation. In providing a semantic framework to describe
> the general categories of behavioral protocol known to test working
> memory, an investigator knowledgeable in that field is saved the often
> tedious task of sorting through the results of a broad, keyword search
> for */working memory/*, whereas one less familiar with the field is
> able to identify the data sets of interest without prior knowledge of
> the specific behavioral paradigm tests. It also covers the fact many
> data sets will be annotated with the specific behavioral paradigm with
> no specific mention of */working memory/. *This works because the
> identified data repositories have been annotated using BIRNLex *and
> *the mediator is capable of using both the preferred terms and lexical
> variants as well as the underlying semantic graph to more efficiently
> identify the desired data sets.
>
>
> On Jan 5, 2007, at 2:02 PM, Susie Stephens wrote:
>
>>
>> Here's a reminder for Monday's BioRDF call.
>>
>> Date of Call: Monday January 8, 2007
>> Time of Call: 11:00am Eastern Time
>> Dial-In #: +1.617.761.6200 (Cambridge, MA)
>> Participant Access Code: 246733 ("BIORDF")
>> IRC Channel: irc.w3.org port 6665 channel #BioRDF
>> Duration: ~1 hour
>>
>> Agenda
>> - Review action items.
>> - Kei Cheung will provide a status update regarding the BMC
>> Bioinformatics paper.
>> - Daniel Rubin will highlight the use of images within scientific
>> queries.
>> - Bill Bug will describe some of the most appropriate use cases from
>> BIRN.
>> - Finalize decisions regarding the best venue for the demo.
>> - AOB.
>>
>>
>>
>
> Bill Bug
> Senior Research Analyst/Ontological Engineer
>
> Laboratory for Bioimaging & Anatomical Informatics
> www.neuroterrain.org
> Department of Neurobiology & Anatomy
> Drexel University College of Medicine
> 2900 Queen Lane
> Philadelphia, PA 19129
> 215 991 8430 (ph)
> 610 457 0443 (mobile)
> 215 843 9367 (fax)
>
>
> Please Note: I now have a new email - William.Bug@DrexelMed.edu
> <mailto:William.Bug@DrexelMed.edu>
>
>
>
>
Received on Monday, 8 January 2007 16:08:57 UTC