- From: Kei Cheung <kei.cheung@yale.edu>
- Date: Mon, 08 Jan 2007 11:08:43 -0500
- To: William Bug <William.Bug@DrexelMed.edu>
- Cc: Susie Stephens <susie.stephens@oracle.com>, public-semweb-lifesci <public-semweb-lifesci@w3.org>, MaryAnn Martone <maryann@ncmir.ucsd.edu>, Jessica Turner <turnerj@uci.edu>
Hi All, I tried to call the BioRDF conference, but I kept getting the message saying my access code "246733" was incorrect. Thanks, -Kei William Bug wrote: > Hi All, > > Here is one Use Case to review for today thanks to the efforts of my > colleagues on the BIRN Ontology Task Force, Maryann Martone and > Jessica Turner. It is representative of the low-hanging fruit approach > we are taking - one where minimal ontology-based annotation on large > data sets using a semantic framework covering specific neuroscience > domains will help us to progressively add more utility to the BIRN > infrastructure appropriate to meet the needs of the broadest range of > neuroscientists. This is also a neuroimaging Use Case, so it should > dovetail nicely with the discussion Daniel Rubin will be leading. > > There are a considerable collection of Use Cases covering a wider > range of topics from molecular data in mouse models to clinical > assessments which we (the BIRN OTF) are now proceeding through to > provide a sufficient amount of detail so as to help us more clearly > define our semantic infrastructural requirements. I'll send more of > these around later as they become available. > > Cheers, > Bill > > > *BIRN Use Case #1:** **Locating specific types of functional > neuroimaging data sets through the BIRN infrastructure* > A researcher wants to examine all fMRI datasets where the subject is > given a working memory task. Through the simple web interface, the > user enters “fMRI data and working memory task”. The BIRN mediator > searches the BIRNLex lexicon+ontology framework to find those > behavioral paradigms listed under working memory tasks. The mediator > then dispatches a distributed query to those data repositories which > have been registered to it in search of fMRI data where subjects have > been administered these tasks. In order to understand the results in > context, the web interface provides the relevant portion of the > hierarchy and indexes each result to the relevant term. > > The mediator in this case performs two essential functions: 1) it > allows a query to be issued across multiple data resources without the > need to query each one separately; 2) it utilizes the knowledge > contained in BIRNLex to expand the query beyond the specified term to > find data that is relevant to the query. > > This use case requires a level of deeper integration than simple > keyword indexing of data sources can provide, because the user is > asking for only those scans from subjects that were given a working > memory test. Simple keyword descriptions of a resource do not > provide adequate information for performing this type of query. For > example, the current description of the data content of the fMRI Data > Center (www.fmridc.org <http://www.fmridc.org>) includes the following: > > anatomical / structural, behavioral.sensory performance.olfaction, > neuroimaging.functional > > Keyword searching would be able to indicate the fMRI data center as > one resource that might have relevant data but would not be able to > return the specific data sets desired without the user performing an > additional query and sorting through the results, weeding out all the > false positives. > > The goal of the BIRN Infrastructure in this context is to provide > enabling technology not only capable off-loading some of the more > simple semantically-driven tasks normally carried out by an expert > neuroscience investigator, but to also provide a general knowledge > supplement to cover those sub-domains a given neuroscientist may not > know in detail. This example demonstrates both such forms of > cognitive augmentation. In providing a semantic framework to describe > the general categories of behavioral protocol known to test working > memory, an investigator knowledgeable in that field is saved the often > tedious task of sorting through the results of a broad, keyword search > for */working memory/*, whereas one less familiar with the field is > able to identify the data sets of interest without prior knowledge of > the specific behavioral paradigm tests. It also covers the fact many > data sets will be annotated with the specific behavioral paradigm with > no specific mention of */working memory/. *This works because the > identified data repositories have been annotated using BIRNLex *and > *the mediator is capable of using both the preferred terms and lexical > variants as well as the underlying semantic graph to more efficiently > identify the desired data sets. > > > On Jan 5, 2007, at 2:02 PM, Susie Stephens wrote: > >> >> Here's a reminder for Monday's BioRDF call. >> >> Date of Call: Monday January 8, 2007 >> Time of Call: 11:00am Eastern Time >> Dial-In #: +1.617.761.6200 (Cambridge, MA) >> Participant Access Code: 246733 ("BIORDF") >> IRC Channel: irc.w3.org port 6665 channel #BioRDF >> Duration: ~1 hour >> >> Agenda >> - Review action items. >> - Kei Cheung will provide a status update regarding the BMC >> Bioinformatics paper. >> - Daniel Rubin will highlight the use of images within scientific >> queries. >> - Bill Bug will describe some of the most appropriate use cases from >> BIRN. >> - Finalize decisions regarding the best venue for the demo. >> - AOB. >> >> >> > > Bill Bug > Senior Research Analyst/Ontological Engineer > > Laboratory for Bioimaging & Anatomical Informatics > www.neuroterrain.org > Department of Neurobiology & Anatomy > Drexel University College of Medicine > 2900 Queen Lane > Philadelphia, PA 19129 > 215 991 8430 (ph) > 610 457 0443 (mobile) > 215 843 9367 (fax) > > > Please Note: I now have a new email - William.Bug@DrexelMed.edu > <mailto:William.Bug@DrexelMed.edu> > > > >
Received on Monday, 8 January 2007 16:08:57 UTC