- From: Joanne Luciano <jluciano@predmed.com>
- Date: Sun, 17 Dec 2006 10:30:48 -0500
- To: Joanne Luciano <jluciano@predmed.com>
- Cc: Kei Cheung <kei.cheung@yale.edu>, Alan Ruttenberg <alanruttenberg@gmail.com>, W3C HCLSIG <public-semweb-lifesci@w3.org>
Correction below: On Dec 17, 2006, at 10:09 AM, Joanne Luciano wrote: > Hi Kei, > > I made my edits on the google page this morning, so this becomes a > belated request for deadline extension. > > Included here: > > 1.3.2. Standards as Applications of Semantic Web Technologies (Joanne) > > > There is a tacit assumption within the Semantic Web community that > every type of data sets and ontologies will be interoperable. The > reality is that a multitude of different conceptualisations and > formal representation of data exist. A key part of the Health and > Life Sciences SIG's vision is that standards need to be established > and accepted sufficiently widely within the community so as to > allow that necessary interoperability between data sets, > application and workflows. A relatively early effort in this > direction was the BioPAX initiative [REFS] which aimed to provide a > common framework for the disparate data sources and multiple > conceptualisations of cellular pathways. Its major success was in > increasing public awareness and persuading a community of > researchers that the integration of data was possible and would > result in major research and discovery advantages. It highlighted > the multiple conceptualizations existing within the domain of > cellular pathways and made people aware of the significant > investment needed to achieve interoperability at not only a > syntactic level but also at a semantic one. A considered critique > of the effort with suggestions of the way forward is presented in > [REF to Luciano and Stevens] in this issue. > > In the medium term future, the efforts for standardization need a > much more careful analysis of the user requirements so as to be > able to get the end users (wet lab scientists) to buy into the > approach and its benefits. A greater understanding is needed both > of the conceptualisations needed which will be reflected in a > number of ontologies and the boundary which lies between what is > possible and useful in OWL based ontologies given the capabilities > of the current generation of reasoners, and on the other hand the > ambitions and needs of clinical researchers to integrate and > interpret their data. > > The HCLSIG has an interesting role in the SW community because > potentially there is a far greater commitment to resourse curation > and the need for standard formats and data integration, thus making > it a much more likely candidate for being a poster child for the > success of Semantic Web technologies. > > Added to Section 2: > > > The following figure shows the respective relationship between the > different task forces and their role in the bench to bedside vision. > > <HCLSIG_paper.jpg> > > and added my contributions to the section at the bottom: > > JL wrote section 1.3.2 and and contributed to section 2 and provided the graphic. > JL Joanne Luciano, Havard Medical School, Universtity of Manchester > (UK), BioPathways Consortium, BioPAX > > Affiliation: > > JL Joanne Luciano, Havard Medical School, Universtity of Manchester > (UK), BioPathways Consortium, BioPAX > > To Acknowledgment > > (after Kei's) JL was supported by NSF grant IIS-0542041. > > ---Joanne > > > On Dec 15, 2006, at 10:58 AM, Kei Cheung wrote: > >> >> Just want to add that the google doc editing deadline is 12:00 am >> (mid-night EST), Dec 15. If people still need a little bit more >> time, please let us know as soon as possible. We might be able to >> extend it to 12:00 noon, Saturday Dec 16 (but not anymore since >> the deadline is very close). >> >> Thanks, >> >> -Kei >> >> Alan Ruttenberg wrote: >> >>> >>> Correction: Helen, Vipul will send whatever they haven't >>> integrated into the googledoc to Alan over the weekend for >>> integration. Alan will edit and send to Kei at weekend's end. >>> >>> -Alan >>> >>> On Dec 14, 2006, at 6:14 PM, Eric Neumann wrote: >>> >>>> [NEW] ACTION: Content will be moved off from googleDoc to Word >>>> COB Dec 15; to be serially edited by Alan, Helen, Vipul, and >>>> returned to Kei Dec 20. [recorded in http://www.w3.org/ >>>> 2006/12/14-hcls- minutes.html#action01 <http://www.w3.org/ >>>> 2006/12/14-hcls- minutes.html#action01> ] >>>> >>> >>> >> >> >> >> > > Joanne Luciano, PhD > Predictive Medicine, Inc. > 45 Orchard Street > Belmont MA 02478-3008 > Email: jluciano@predmed.com > > > Joanne Luciano, PhD Predictive Medicine, Inc. 45 Orchard Street Belmont MA 02478-3008 Email: jluciano@predmed.com
Received on Sunday, 17 December 2006 16:21:26 UTC