Re: existing semantic models for normal conditions of metabolites in bodily fluids?

Seems like you are looking for a modeling approach that support reference
ranges.  You might check here http://mlhim.org/documents.html


On Sat, Aug 13, 2016 at 3:50 PM, Jim McCusker <mccusker@gmail.com> wrote:

> I've been using UBERON for anatomical parts and SIO's
> attribute/measurement approach for metabolites, using CHEBI to classify the
> chemical types. The sample (urine, for example,
>
> :X a sio:Sample, UBERON:Urine;
> sio:hasPart [
> a CHEBI:Creatinine;
> sio:hasAttribute [
> a sio:Concentration;
> sio:hasValue 2.3;
> sio:hasUnit uo:ug/mL
> ];
> ].
>
> I don't have the right URIs here for UO, UBERON, or CHEBI, of course.
>
> Jim
>
> On Sat, Aug 13, 2016 at 11:19 AM Egon Willighagen <
> egon.willighagen@gmail.com> wrote:
>
>> Hi all,
>>
>> I'm extracting some metabolite-disease relationships and the book I'm
>> reading also lists normal concentrations metabolites in various bodily
>> fluids for various age groups.
>>
>> For example, for Phe 0-1 years in serum it lists <80 micromolar
>> ("newborns" is another age group, but most are like "x-y years").
>>
>> Has anyone encoded such information in a semantic manner already? What
>> should I be reading?
>>
>> Looking forward to hearing from you,
>>
>> grtz,
>>
>> Egon
>>
>> --
>> E.L. Willighagen
>> Department of Bioinformatics - BiGCaT
>> Maastricht University (http://www.bigcat.unimaas.nl/)
>> Homepage: http://egonw.github.com/
>> LinkedIn: http://se.linkedin.com/in/egonw
>> Blog: http://chem-bla-ics.blogspot.com/
>> PubList: http://www.citeulike.org/user/egonw/tag/papers
>> ORCID: 0000-0001-7542-0286
>> ImpactStory: https://impactstory.org/EgonWillighagen
>>
>> --
> James P. McCusker III, Ph.D.
> http://tw.rpi.edu/web/JamesMcCusker
>



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Timothy W. Cook, President
Data Insights, Inc.

Received on Saturday, 13 August 2016 23:33:01 UTC