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Re: [COI] CT#8 Drug Information Needed for Test Case Query

From: Matt Williams <matthew.williams@cancer.org.uk>
Date: Thu, 12 Jun 2008 20:57:02 +0100
Message-ID: <48517F8E.1030505@cancer.org.uk>
To: helen.chen@agfa.com
CC: "R.Cornet@amc.uva.nl" <R.Cornet@amc.uva.nl>, "public-semweb-lifesci@w3.org" <public-semweb-lifesci@w3.org>

Dear Helen,

I'd be very interested in how you get on. I can't see how to extract a 
SNOMED-CT ID from RxNorm in the navigator, but I'm sure it can be done 
from the dataset.

More generally, I'm interested why you didn't use drug names from 
something like Pubmed (I'm sure there's a reason - I just don't know 
what it is).

Thanks,

Matt

helen.chen@agfa.com wrote:
> 
> Ronald
> 
> I checked RxNav and it is a good tool to get most of information we 
> needed for the COI test case.
> 
> I will check the mapping between RxNorm ingredients and SNOMED to see 
> how we can get the link between, for example "anticoagulants" to 
> detailed drug names in RxNORM.    
> 
> Thanks for the pointer and good suggestions.
> 
> Helen
> 
> 
> 
> 
> *"Ronald Cornet" <r.cornet@amc.uva.nl>*
> Sent by: public-semweb-lifesci-request@w3.org
> 
> 11/06/2008 02:22 PM
> Please respond to
> "R.Cornet@amc.uva.nl" <R.Cornet@amc.uva.nl>
> 
> 
> 	
> To
> 	"public-semweb-lifesci@w3.org" <public-semweb-lifesci@w3.org>
> cc
> 	
> Subject
> 	RE: [COI] CT#8 Drug Information Needed for Test Case Query
> 
> 
> 	
> 
> 
> 
> 
> 
> 
> Helen,
>  
> Looking at RxNorm via RxNav _http://mor.nlm.nih.gov/download/rxnav/_
> Here the brand names below can be mapped to ingredients.
>  
> Looking up the ingredients in SNOMED shows their classes.
>  
> So it seems that adequately combining the two can do the job.
>  
> Regards, Ronald
>  
> 
> ###############################################################
> Ronald Cornet, PhD                    email: R.Cornet@amc.uva.nl
> dept. of Medical Informatics          phone: +31 (0)20 566 5188
> Academic Medical Center, Room J1B-115 fax:   +31 (0)20 691 9840
> P.O.Box 22700                         www: 
> _http://kik.amc.uva.nl/home/rcornet/_
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> The Netherlands                       'The truth is out there'
> 
>  
> 
> ------------------------------------------------------------------------
> *From:* public-semweb-lifesci-request@w3.org 
> [mailto:public-semweb-lifesci-request@w3.org] *On Behalf Of 
> *helen.chen@agfa.com*
> Sent:* Wednesday, June 11, 2008 16:34*
> To:* public-semweb-lifesci@w3.org*
> Subject:* [COI] CT#8 Drug Information Needed for Test Case Query
> 
> 
> Eric
> 
> As a minimal requirement to get the test case working In the CT#8 [1], 
> we need to identify the following drug information.  I did some text 
> search in your Medicaiton_DE.txt [2] file and found some examples of 
> drug names under each category
> *
> 1. Metfomin, Insulin secretagogue, or Alpha-glucosidase inhibitors* *
> drug names: *Metformin, Repaglinide, Gliclazide, Glipizide, Acarbose, 
> Miglitol *
> 2. Insulin therapy* *
> drug names: *Aimsco Insulin Syringe, *
> 3. Rosiglitazone or Proglitazone* *
> drug names: *Avandia, Actos *
> 4. corticosteriods treatment* *
> drug names: *Prelone, Medrol, Deltasone, Kenalog, etc *
> 5.  weightloss drugs* *
> drug names: *Xenical, Meridia, Tenuate, Tepanil, Adipex-P, Fastin, 
> Phentermine HCl , etc *
> 6. nonsteroidal anti-inlammatory drugs* *
> drug names: *Ibuprogen, Naproxen Sodium , Diclofenac Potassium, 
> Diclofenac Sodium, etc *
> 7. anticoagulants* *
> drug names: *Coumadin, Plavix, Heparin, etc *
> 8. uricosuric medication* *
> drug names: *Benuryl, Benemid, Probalan, Anturane *
> * 
> 
> Your Medication.DE file seems to contain drug name and package 
> information, but as you can see, there is no "drug" class relationship 
> that represents the above relationship.  I doubt we can find such 
> categorization relationship in RxNorm.  
> 
> For the demonstration purpose, we can construct a small "drug" ontology 
> to cover the above concepts and drug names.  
> 
> But the ideal way is to use an existing and well developed drug ontology 
> for this purpose.  
> 
> Does anyone on the list know such ontology?
> 
> Kind Regards,
> 
> 
> [1] 
> http://esw.w3.org/topic/HCLS/ClinicalObservationsInteroperability/SPARQL8.html 
> 
> [2] http://www.w3.org/2008/04/DiabeticPatientsDataSet/Medication_DE.txt
> 
> *
> Helen Chen | **Agfa HealthCare*
> Senior Researcher | HE/Advanced Clinical Applications Research
> T  +1 519 746 6210 Ext.3186 | M  +1 519 498 6244
> 
> Agfa HealthCare Inc., 455 Phillip Street, Waterloo, ON N2L 3X2, Canada_
> __http://www.agfa.com/healthcare/_
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Received on Thursday, 12 June 2008 19:57:47 GMT

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