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RE: Computers may predict drugs’ side effects

From: Lin MD, Simon <LINMD.SIMON@mcrf.mfldclin.edu>
Date: Tue, 12 Jun 2012 15:49:47 +0000
To: Joanne Luciano <jluciano@gmail.com>, public-semweb-lifesci hcls <public-semweb-lifesci@w3.org>
Message-ID: <A5BD550FC766564987DA2A59779890300D50189C@MCL-EXMB02.mfldclin.org>
Hi Joanne,

Thank you for sharing this topic with the group! For discussion, I am attaching the manuscript and a related review article. 

Generally, the prediction models work well in this problem domain (-- If not, the discipline of medicinal chemistry would not exist). 

The bottleneck is the availability of large scale data: chemical structure, drug target, protein-protein interaction, indications, know side effects, etc. 

As such, Open Linked Data might offer help!

Best regards,

Simon

==================================================
Simon Lin, MD
Director, Biomedical Informatics Research Center 
Marshfield Clinic Research Foundation 
1000 N Oak Ave, Marshfield, WI 54449 
Office 715-221-7299 
Lin.Simon@mcrf.mfldclin.edu 
www.marshfieldclinic.org/birc

For scheduling assistance, please contact
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      715-221-6403


-----Original Message-----
From: Joanne Luciano [mailto:jluciano@gmail.com] 
Sent: Tuesday, June 12, 2012 10:02 AM
To: public-semweb-lifesci hcls
Subject: Computers may predict drugs’ side effects

FYI

I know some of you would be interested in this -- and maybe some of you know more details that can be shared?

http://articles.boston.com/2012-06-11/business/32177397_1_side-effects-adverse-drug-reactions-study-of-drug-development

Joanne


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Received on Tuesday, 12 June 2012 15:50:33 GMT

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