NCBO Webinar: Chris Stoeckert, April 6

The next NCBO Webinar will be presented by Dr. Chris Stoeckert from the
University of Pennsylvania on "Using ontologies in integrative tools for
protozoan parasite research" at 10:00am PT, Wednesday, April 6.  Below is
information on how to join the online meeting via WebEx and accompanying
teleconference. For the full schedule of the NCBO Webinar presentations see:
http://www.bioontology.org/webinar-series.


ABSTRACT:
Protozoan parasites such as those that cause malaria and toxoplasmosis
remain major threats to global health, and a significant biodefense
concern.  Current treatments are limited and sometimes compromised by
acquired resistance. Solutions will come from the integration and mining of
ongoing research. The need for data integration is common among research
communities tackling complex topics such as the biology of eukaryotic
pathogens, their interaction with hosts, and the search for druggable
targets and vaccine candidates. Biomedical researchers have greatly
benefited from the Gene Ontology (GO) that provides standardized terms for
annotating protein function, location, and participation in processes. GO
and other relevant ontologies have largely been developed to support human
and model organism biology with only limited representation of protozoan
parasite biology. In addition, the availability and use of standard terms is
also very limited for the inputs and outputs of bioinformatic tools that are
commonly used to analyze protozoan parasite datasets and is a barrier for
linking these tools together. In the Integrative Tools for Protozoan
Parasite Research (ITPPR) project, we have started addressing these areas by
developing tools needed by the communities served by EuPathDB (
http://eupathdb.org/). We are using ontology-based models as part of our
process to build tools for collecting information on isolates, describing
phenotypic outcomes of transgenic parasites, and for joining web services
running sequence similarity and alignment analysis. Ontologies are drawn
from the OBO Foundry and include the Infectious Disease Ontology (IDO) and
OBI (Ontology for Biomedical Investigations).


SPEAKER BIO:
Chris Stoeckert is a Research Professor of Genetics at the University of
Pennsylvania and a core member of the Center for Bioinformatics. His
research is in genomics and functional genomics data integration covering
databases, standards and ontologies, and data modeling and analysis. He
directs CBIL (Computational Biology and Informatics Lab) that has developed
the GUS database system. He is a co-investigator of the EuPathDB
Bioinformatics Resource Center (eupathdb.org) that supports protozoan
parasite research with sites like PlasmoDB (plasmodb.org). He also leads the
Beta Cell Genomics (genomics.betacell.org) component of the Beta Cell
Biology Consortium. He is president of the Functional Genomics Data Society
(formerly known as MGED), led the effort to build the MGED Ontology (MO),
and is an active developer of the Ontology for Biomedical Investigations
(OBI). With David Roos and his group, he has developed OrthoMCL to generate
groups of orthologous genes.


WEBEX DETAILS:
Topic: NCBO Webinar Series
Date: Wednesday, April 6, 2011
Time: 10:00 am, Pacific Daylight Time (San Francisco, GMT-07:00)
Meeting Number: 926 719 478
Meeting Password: ncbo


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