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Re: SenseLab note: some updates

From: Kei Cheung <kei.cheung@yale.edu>
Date: Thu, 15 May 2008 19:39:45 -0400
Message-ID: <482CC9C1.3090105@yale.edu>
To: "Kashyap, Vipul" <VKASHYAP1@PARTNERS.ORG>
CC: Alan Ruttenberg <alanruttenberg@gmail.com>, Matthias Samwald <samwald@gmx.at>, public-semweb-lifesci@w3.org

Hi Vipul,

Take the snomed term "Alzheimer's disease" (AD), for example. One axis 
may be used to indicate the progression of the disease. For example, 
http://www.memorystudy.org/alzheimers_stages.htm lists 7 stages of 
Alzheimer's disease: no memory loss symptom, very mild, mild, moderate, 
moderately severe, severe, and very severe.

In gene ontology (GO), "memory" (or "learning") is a term under 
biological process, one may want to give it a modifier such as 
"impaired" if we want to use GO in combination with some modifier 
ontology to describe an AD phenotype (e.g., "impaired memory").

Just want to give some examples to illustrate the post-coordinated approach.

Cheers,

-Kei

Kashyap, Vipul wrote:

>Kei,
>
>It's interesting that you bring up this notion.
>
>Most of the vocabularies in healthcare tend to be pre-coordinated, e.g., ICD9,
>CPT4.
>However there some compositional terminologies such as RxNorm and LOINC which
>has an underlying 
>model with 6 axes. Snomed tries to be a post-coordinated terminology, but in
>reality it is partially
>pre-coordinated and partially post-coordinated.
>
>Cheers,
>
>---Vipul
>
>  
>
>>-----Original Message-----
>>From: public-semweb-lifesci-request@w3.org 
>>[mailto:public-semweb-lifesci-request@w3.org] On Behalf Of Kei Cheung
>>Sent: Tuesday, May 13, 2008 12:51 PM
>>To: Alan Ruttenberg
>>Cc: Matthias Samwald; public-semweb-lifesci@w3.org
>>Subject: Re: SenseLab note: some updates
>>
>>
>>Sounds to me like an ontology exercise. For example, pre-coordinated 
>>approach (knowledgebase) vs. post-coordinated approach 
>>(knowledge base)? 
>>May not be a good analogy since I'm not an ontology expert. :-) 
>>
>>However, I wonder to what extent these two ontology 
>>approaches have been 
>>(or have not been) applied to the construction of ontologies 
>>involved in 
>>the "knowledge base" or "knowledgebase" that we are talking 
>>about here.
>>
>>-Kei
>>
>>Alan Ruttenberg wrote:
>>    
>>
>>>Knowledge base is generally written as two words. Try a 
>>>      
>>>
>>google fight 
>>    
>>
>>>on scholar.google.com.
>>>-Alan
>>>
>>>On May 13, 2008, at 8:31 AM, Matthias Samwald wrote:
>>>
>>>      
>>>
>>>>I have made some small updates to the draft SenseLab conversion 
>>>>document based on feedback from members of the group. See
>>>>http://www.w3.org/2001/sw/hcls/notes/senselab/
>>>>
>>>>Some added text is highlighted in green. Several minor changes are 
>>>>not highlighted.
>>>>
>>>>Cheers,
>>>>Matthias Samwald
>>>>DERI Galway, Ireland // Semantic Web Company, Austria
>>>>http://www.deri.ie/
>>>>http://www.semantic-web.at/
>>>>
>>>>
>>>>
>>>>        
>>>>
>>>      
>>>
>>
>>
>>    
>>
>
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Received on Thursday, 15 May 2008 23:44:35 UTC

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