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RE: [COI] CT#8 Drug Information Needed for Test Case Query

From: Ronald Cornet <r.cornet@amc.uva.nl>
Date: Wed, 11 Jun 2008 20:22:39 +0200
To: "public-semweb-lifesci@w3.org" <public-semweb-lifesci@w3.org>
Message-ID: <20080611202239881.00000002672@06-020-2539>
Helen,
 
Looking at RxNorm via RxNav http://mor.nlm.nih.gov/download/rxnav/
Here the brand names below can be mapped to ingredients.
 
Looking up the ingredients in SNOMED shows their classes.
 
So it seems that adequately combining the two can do the job.
 
Regards, Ronald
 

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Ronald Cornet, PhD                    email: R.Cornet@amc.uva.nl
dept. of Medical Informatics          phone: +31 (0)20 566 5188
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________________________________

	From: public-semweb-lifesci-request@w3.org [mailto:public-semweb-lifesci-request@w3.org] On Behalf Of helen.chen@agfa.com
	Sent: Wednesday, June 11, 2008 16:34
	To: public-semweb-lifesci@w3.org
	Subject: [COI] CT#8 Drug Information Needed for Test Case Query
	
	

	Eric 
	
	As a minimal requirement to get the test case working In the CT#8 [1], we need to identify the following drug information.  I did some text search in your Medicaiton_DE.txt [2] file and found some examples of drug names under each category 
	
	1. Metfomin, Insulin secretagogue, or Alpha-glucosidase inhibitors 
	drug names: Metformin, Repaglinide, Gliclazide, Glipizide, Acarbose, Miglitol 
	2. Insulin therapy 
	drug names: Aimsco Insulin Syringe, 
	3. Rosiglitazone or Proglitazone 
	drug names: Avandia, Actos 
	4. corticosteriods treatment 
	drug names: Prelone, Medrol, Deltasone, Kenalog, etc 
	5.  weightloss drugs 
	drug names: Xenical, Meridia, Tenuate, Tepanil, Adipex-P, Fastin, Phentermine HCl , etc 
	6. nonsteroidal anti-inlammatory drugs 
	drug names: Ibuprogen, Naproxen Sodium , Diclofenac Potassium, Diclofenac Sodium, etc 
	7. anticoagulants 
	drug names: Coumadin, Plavix, Heparin, etc 
	8. uricosuric medication 
	drug names: Benuryl, Benemid, Probalan, Anturane 
	  
	
	Your Medication.DE file seems to contain drug name and package information, but as you can see, there is no "drug" class relationship that represents the above relationship.  I doubt we can find such categorization relationship in RxNorm.   
	
	For the demonstration purpose, we can construct a small "drug" ontology to cover the above concepts and drug names.   
	
	But the ideal way is to use an existing and well developed drug ontology for this purpose.   
	
	Does anyone on the list know such ontology?
	
	Kind Regards,
	
	
	[1] http://esw.w3.org/topic/HCLS/ClinicalObservationsInteroperability/SPARQL8.html 
	[2] http://www.w3.org/2008/04/DiabeticPatientsDataSet/Medication_DE.txt 
	
	
	Helen Chen | Agfa HealthCare
	Senior Researcher | HE/Advanced Clinical Applications Research
	T  +1 519 746 6210 Ext.3186 | M  +1 519 498 6244
	
	Agfa HealthCare Inc., 455 Phillip Street, Waterloo, ON N2L 3X2, Canada
	http://www.agfa.com/healthcare/ <http://www.agfa.com/healthcare/> 
	
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Received on Wednesday, 11 June 2008 18:23:55 GMT

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