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[coi] Some classifications of the entities in patient 1

From: Alan Ruttenberg <alanruttenberg@gmail.com>
Date: Tue, 12 Feb 2008 10:46:06 -0500
Message-Id: <C699210B-86E2-4386-9721-1F7DC3C678A9@gmail.com>
Cc: Werner Ceusters <ceusters@buffalo.edu>, Barry Smith <phismith@buffalo.edu>
To: public-semweb-lifesci@w3.org

Very rough, for discussion. From the realist point of view.

Patient 1 in http://esw.w3.org/topic/HCLS/ 
ClinicalObservationsInteroperability/MockedUpPatientData

dispositions:
   orthostatic intolerance http://en.wikipedia.org/wiki/ 
Orthostatic_intolerance
   dizziness D004244
   hypertension D006973
   orthostatic hypotension D007024
   dizziness while standing - while standing = condition on realization
   fainting while standing
   diabetes

Uncertain:
   pulse rate (see http://groups.google.com/group/bfo-discuss/ 
browse_thread/thread/1695b1b7780ea455)
   cardiac ejection fraction ("quality of an occurrent" ?)

Qualities:
   Hemoglobin A1c 9 % D006442 (the protein), need a glycosylated version
     (the quality is actually A1C form glycosylated heamoglobin/  
total  haemoglobin) (see https://wiki.cbil.upenn.edu/obiwiki/ 
index.php/ConcentrationQualityInOBI, https://wiki.cbil.upenn.edu/ 
obiwiki/index.php/Image:Concentration.pdf)
   postprandial glucose
   serum creatinine
   urinary protein
   BP was 84/60 mm Hg (maybe a disposition, not sure) Barry's view in  
2003 http://ontology.buffalo.edu/medo/BPO.pdf

IndependentContinuants
Patient
Bicycle
  Drugs (always material with some therapeutic role)
   valsartan 80 mg
   insulin
   atenolol dose 6.25
   beta blocker
cerebral infarction
cerebellar infarction
ischemic lesionn
brain

Organizations
   Jichi Medical School Hospital
   Hypertension Clinic (implicit building, space, physicians)

TemporalRegions
54 years old
2002
2004
13 February 2005

Processes
http://en.wikipedia.org/wiki/Valsalva_maneuver
having Echocardiography
having a brain MRI
having single photon emission computed tomography (SPECT)
complaining
once daily dose
Life of patient 1
drug therapies
falling down
riding a bicycle
diagnosis
head-up tilt test
sleep
Walking

Functions
Ability to walk ("ambulatory")

Information entities (all information entities here are "about" some  
occurrent or continuant)
single photon emission computed tomography (SPECT) images
Electrocardiogram
MRI images
84%
2+
84.0 mumol/l (note for this and other measurements we have the  
information entity and the quality the information entity is "about")
173/93

~~~~

http://ontology.buffalo.edu/medo/BPO.pdf

Blood pressure is the pressure exerted on the arterial walls by the  
flow of blood. The
term ‘blood pressure’ designates both a certain function (to exert  
pressure) and also
a certain state (of pressure being exerted), both of which are  
dependent continuants,
the latter being associated with a value. The process of change in  
this value is an
occurrent, which is dependent on the underlying state. Like all other  
functions in the
body, blood pressure is subject to regulation. Regulation of blood  
pressure involves
the exercise of a number of different functions in different parts of  
the body. Their
collective task is to maintain blood pressure value within a certain  
interval. 
  
Received on Tuesday, 12 February 2008 15:46:28 GMT

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