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RE: Sample protocols and possible strategy

From: Kashyap, Vipul <VKASHYAP1@PARTNERS.ORG>
Date: Mon, 8 Oct 2007 22:19:36 -0400
Message-ID: <DBA3C02EAD0DC14BBB667C345EE2D124010F003B@PHSXMB20.partners.org>
To: "Rachel Richesson" <Rachel.Richesson@epi.usf.edu>, "Dan Corwin" <dan@lexikos.com>
Cc: "public-semweb-lifesci hcls" <public-semweb-lifesci@w3.org>, "Stanley Huff" <Stan.Huff@intermountainmail.org>, "Yan Heras" <Yan.Heras@intermountainmail.org>, "Oniki, Tom (GE Healthcare, consultant)" <Tom.Oniki@ge.com>, "Joey Coyle" <joey@xcoyle.com>, "Landen Bain" <lbain@topsailtech.com>, "Bron W. Kisler" <bkisler@earthlink.net>


Thanks for the hard work! I guess the next step is to look at these protocols
and come up with a list of requirements.


A demonstration from one standard (clinical research) information model to a
single healthcare information model (Dr. Huff's detailed clinical models, DCM)
could at least demonstrate the value of a standard clinical research information
model and might even facilitate its adoption...


[VK] This could be a pragmatic goal for this group in the short term. However,
it's not easy as it sounds.

Either way, I believe that an early task for our group should be to identify
what information model is most likely to represent Protocol Eligibility in a
standardized way. I do not believe that the CDISC's SDTM is the best model, but
I could be wrong. I am fairly certain that *all* the CDISC models will
eventually become harmonized with the BRIDG model
(https://cabig.nci.nih.gov/News_Folder/BRIDG_v1.0_Release/ ) , which is planned
to harmonize w HL7 models as well.  


[VK] It may not be easy to "guess" a Protocol Eligibility Information Model. A
methodical way to do it would be draw up a list of functional requirements and
see to what extent each of the models mentioned above satisfy them.


So, I wonder if one strategy might be to use the BRIDG as a starting point - map
sample protocols to BRIDG as case exemplars, and then map the appropriate BIRDG
constructs to the DCM models in some general, re-usable way ....


[VK] Determining a starting point may not be a bad idea. May make sense to
analyze which of the information models discussed support the requirements
distilled from the use cases.


I look forward to talking on this topic tomorrow.  Meanwhile, another
outstanding task for me is to think of definitions/measures of "success" for
this project. If anyone has suggestions, please direct them to me.


[VK] One definition of "success" could be that we achieve the pragmatic goal
satisfied above?





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Received on Tuesday, 9 October 2007 02:19:55 UTC

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