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RE: protein entities (was Re: Rules (was Re: Ambiguous names. was: Re: URL +1, LSID -1)

From: Michel_Dumontier <Michel_Dumontier@carleton.ca>
Date: Thu, 19 Jul 2007 18:20:34 -0400
To: satya30@uga.edu, Michel_Dumontier <Michel_Dumontier@carleton.ca>, Darren Natale <dan5@georgetown.edu>
Cc: Eric Jain <Eric.Jain@isb-sib.ch>, Alan Ruttenberg <alanruttenberg@gmail.com>, Chris Mungall <cjm@fruitfly.org>, Bijan Parsia <bparsia@cs.man.ac.uk>, public-semweb-lifesci hcls <public-semweb-lifesci@w3.org>
Message-id: <AB349814F1ECB143A5D4CD29C7A645690187DFC4@CCSEXB10.CUNET.CARLETON.CA>

> Many post-translational modifications like glycosylation
> (http://www.functionalglycomics.org/static/index.shtml)in proteins
> fundamentally change the (functional) 'nature' of the protein (as also
the
> molecular structure of the protein in case of glycosylation through
> addition of sugar chains (glycans)).

Absolutely, but I would go further and state that any chemical
modification will change the fundamental type, and this will necessarily
change dispositions to realizing certain functions.

-=Michel=-
Received on Thursday, 19 July 2007 22:20:55 GMT

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