Individuals described using the ontology for the subcellular anatomy of the nervous system
Subcellular Anatomy Ontology (SAO) Individuals
Maryann Martone, Lisa Fong, Stephen D. Larson, Sarah M. Maynard
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 3A
Lewy Body in a nerve cell in the substantia nigra double-stained for alpha-Synuclein (antibody PER2) and ubiquitin; human/Parkinson's Disease
Baba M et al. 1998. Aggregation of alpha-Synuclein in Lewy Bodies of Sporadic Parkinson's Disease and Dementia with Lewy Bodies. American Journal of Patholofy 152(4):879-884. Figure 1A
need to say in pigmented neurons of substantia nigra
brainstem Lewy body in pigmented neurons of substantia nigra stains for alpha-synuclein; human/dementia with Lewy bodies
Transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and thy-1 promoters
correct to say is_Component of Neuron? (alpha-synuclein is accumulated in Neurons)
Rockenstein et al. Differential Neuropathological Alteratins in Transgenic Mice Expressing alpha-synuclein From the Platetelet-derived Growth Factor and Thy-1 Promoters [citing: Wakabayashi et al., 1998; Spillantini et al., 1998]
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 2B
alpha-Synuclein positive Lewy neurite in substantia nigra stained with PER2; human/dementia with Lewy bodies
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 3G
Intraneuritic Lewy neurite double stained for alpha-synuclein (antibody PER1) in cingulate cortex; human/dementia with Lewy bodies
Lippa et al. 2007. DLB and PDD boundry issues: Diagnosis, treatment, molecular pathology, and biomarkers. Neurology 68:812-819.
Baba M et al. 1998. Aggregation of alpha-Synuclein in Lewy Bodies of Sporadic Parkinson's Disease and Dementia with Lewy Bodies. American Journal of Patholofy 152(4):879-884. Figure 1D
Lewy body stains for alpha-synuclein in cytoplasm of dopaminergic substantia nigra neurons; human/dementia with Lewy bodies
Sheng JG et al. 1997. Neuritic plaque evolution in Alzheimer's disease is accompanied by transition of activated microglia from primed to enlarged to phagocytic forms. Acta Neuropathol 94:1-5.
Lewy Neurites stain for alpha-synuclein.
Tofaris et al. 2005. Alpha-Synuclein Dysfunction in Lewy Body Diseases. Vol 20 Suppl. 12 pp S37-S44.
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 2A
alpha-Synuclein positive Lewy bodies in substantia nigra stained with PER1; human/dementia with Lewy bodies
Lewy body in a nerve cell in the substantia nigra stianed only for alpha-synuclein (antibody PER2); human/Parkinson's Disease
Baba M et al. 1998. Aggregation of alpha-Synuclein in Lewy Bodies of Sporadic Parkinson's Disease and Dementia with Lewy Bodies. American Journal of Patholofy 152(4):879-884. Figure 1B
Lewy body in cingulate cortex (neocortex) stained for alpha-synuclein; human/dementia with Lewy bodies
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 3B
Lewy Body double-stained for alpha-Synuclein (antiboty PER2) and ubiquitin in a nerve cell in the substantia nigra. The halo of the Lewy body is strongly immoreactive for alpha-synuclein. (3 Lewy Bodies in this figure)
Masliah et al. 2000. Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders. Science 18. Vol 287(5456):1265-1269.
example schwann cell paranodal termination 1
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 3C
Lewy Body in nerve cell in the substantia nigra double-stained for alpha-synuclein (antibody PER1) and ubiquitin; human/Parkinson's Disease
Lewy neurite stained for alpha-synuclein by using antibody PER1; human/Parkinson's Disease
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 3E
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 3D
Lewy neurite in substantia nigra double-stained for alpha-synuclein and ubiqutin; human/Parkinson's Disease
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 4(A and B)
Small clumps of alpha-synuclein filaments in cingulated cortex; human/dementia with Lewy bodies
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 2E
alpha-Synuclein positive intraneuritic Lewy Body in a Lewy Neurite in the substantia nifra stained with PER2; human/dementia with Lewy bodies
The alpha-synuclein is stained in the core of Lewy Body.
The corona of the Lewy Body stains for alpha-synuclein.
Vicker JC et al. 2003. Direct determination of the proportion of intra- and extra-cellular neocortical neurofibrillary tangles in Alzheimer's disease. Brain Research 971:135-137. Figure 1
Neurofibrillary trangle with tau and MAP2, located in nerve cell body in neocortex
specifically: "amyloid deposit" that is diffuse
would it be correct to say Autophagosome has_Component Mitochondrion if instance is "Mitochondria found in Autophagosomes" ?
specifics: axotomy of superior cervical ganglion (SCG) neurons in adult rats
Rubinsztein DC et al. 2005. Autophagy and Its Possible roles in Nervous System Diseases, Damage and Repair. Autophagy 1(1):11-22.
alpha-Synuclein positive Lewy neurite in hippocampus stained with antibody PER1; human/dementia with Lewy bodies
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 2D
Baba M et al. 1998. Aggregation of alpha-Synuclein in Lewy Bodies of Sporadic Parkinson's Disease and Dementia with Lewy Bodies. American Journal of Patholofy 152(4):879-884. Figure 1L
alpha-synuclein positive abnormal neurites in temporal neocortex; human/dementia with Lewy bodies
McKeith I. 2002. Dementia with Lewy bodies. British Journal of Psychiatry 180:144-147.
Forno LS. Neuropathologic Features of Parkinson's, Huntington's, and Alzheimer's Diseases. Annals New York Academy of Sciences
The neuritic plaque has an amyloid core stained with Luxol fast blue-Bielschowsky silver stain
Intraneuronal Lewy Body double stained for alpha-synuclein (antibody PER1) and ubiquitin in cingulate cortex; human/dementia with Lewy bodies
Trojanowski JQ, Lee VM. 1994. Phosphorylation of neuronal cytoskeletal proteins in Alzheimer's disease and Lewy body dementias. Ann NY Acad Sci 747:92-109
Core has_Component filaments (a matted meshwork of filaments)
Lewy Body in nerve cell in substantia nigra stained for alpha-synuclein (antibody PER1); human/Parkinson's Disease
alpha-Synuclein positive Lewy body in substantia nigra stained with PER2; human/dementia with Lewy bodies
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 3F
Lewy neurite stained for alpha-synuclein by using antibody PER2
Baba M et al. 1998. Aggregation of alpha-Synuclein in Lewy Bodies of Sporadic Parkinson's Disease and Dementia with Lewy Bodies. American Journal of Patholofy 152(4):879-884. Figure 1M
Lewy neurites positive for alpha-Synuclein; human/dementia with Lewy bodies
tau-positive neuropil threads in CA2/3 region of hippocampus
correct to say is_Component of Oligodendrocyte? (alpha-synuclein is accumulated in Oligodendrocytes)
alpha-synuclein positive Lewy body in temporal neocortex
Gai WP et al. 1996. Microtubule-associated protein 5 is a component of Lewy bodies and Lewy neurites in the brainstem and forebrain regions affected in Parkinson's Disease 91:78-81.
located in brainstem, basal forebrain, and cortex
located around ubiquitin-positive region
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 2C
alpha-Synuclein positive Lewy neurite in substantia nigra stained with PER1; human/dementia with Lewy bodies
alpha-synuclein filament in cingulate cortex; human/dementia with Lewy bodies
Spillantini MG, Crowther RA, Jakes R. Hasegawa M. 1998. Alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc. Natl. Acad. Sci. USA 95(May):6469-6473. Figure 4C
The corona has spherical accumulations of filaments (arranged in loose, radiating way)
Riederer B et al. 1986. MAP5: a novel brain microtubule-associated protein under strong developmental regulation. JNeurocytol 15:763-775.
van der Putten H, et al. 2000. Neuropathology in Mice Expressing Human alpha-synuclein. The Journal of Neuroscience 20(16):6021-6029.
ulabeled paired helical filament in cingulate cortex; human/dementia with Lewy bodies