RE: [COI] Clinical Observations Interoperability Telcon January 15 2008

 

	From: Samson Tu [mailto:swt@stanford.edu] 
	
	In the SAGE project, the approach we took was that (1) patient data are
represented by information model entities derived from HL7 RIM, (2) legal
patient data are constrained by DCM, (3) standard terminologies such as SNOMED
CT provides codes used in instances of information model entities, (4) criteria
are logical expressions composed from HL7 data types, variables, functions, and
queries on information structures.We had a collection of templates for logical
expressions that correspond to stereotypical GELLO expressions.
	 
	[VK] Is there a write up or document discussing the above approach,
hopefully with some illustrative examples? 
	Also, would it be possible for you to present these ideas on an upcoming
COI call?  

					How do you plan to deal with the
open-world-assumption problem? If an eligibility criterion says the patient
should not be taken certain drug, do you have to write closure axioms for every
patient?
					 
					[VK]  This is an interesting issue and
maybe we could evolve some best practices on "open world issues in eligibility
criteria". The current approach I have seen is proving that no model exists for
the negation of Exclusion criteria.
					Not sure whether this is generalizable.
					 
					Also, the terminology - information
model distinction appears to be an artificial one, at least from the OWL/DL
perspective. There is no reason why both of them cannot be represented in an OWL
reasoner.
					 
					Cheers,
					 
					---Vipul


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